Dynein light chain LC8 alleviates nonalcoholic steatohepatitis by inhibiting NF-&#954;B signaling and reducing oxidative stress.

Lee, Gong-Rak; Lee, Hye In; Kim, Narae; Lee, Jiae; Kwon, Minjeong; Kang, Ye Hee; Song, Hyeong Ju; Yeo, Chang-Yeol; Jeong, Woojin

Dynein light chain LC8 alleviates nonalcoholic steatohepatitis by inhibiting NF-κB signaling and reducing oxidative stress.

Lee, Gong-Rak; Lee, Hye In; Kim, Narae; Lee, Jiae; Kwon, Minjeong; Kang, Ye Hee; Song, Hyeong Ju; Yeo, Chang-Yeol; Jeong, Woojin.

Afiliação

Lee GR; Department of Life Science and the Research Center for Cellular Homeostasis, Ewha Womans University, Seoul, Korea.
Lee HI; Department of Life Science and the Research Center for Cellular Homeostasis, Ewha Womans University, Seoul, Korea.
Kim N; Department of Life Science and the Research Center for Cellular Homeostasis, Ewha Womans University, Seoul, Korea.
Lee J; Department of Life Science and the Research Center for Cellular Homeostasis, Ewha Womans University, Seoul, Korea.
Kwon M; Department of Life Science and the Research Center for Cellular Homeostasis, Ewha Womans University, Seoul, Korea.
Kang YH; Department of Life Science and the Research Center for Cellular Homeostasis, Ewha Womans University, Seoul, Korea.
Song HJ; Department of Life Science and the Research Center for Cellular Homeostasis, Ewha Womans University, Seoul, Korea.
Yeo CY; Department of Life Science and the Research Center for Cellular Homeostasis, Ewha Womans University, Seoul, Korea.
Jeong W; Department of Life Science and the Research Center for Cellular Homeostasis, Ewha Womans University, Seoul, Korea.

J Cell Physiol ; 237(9): 3554-3564, 2022 09.

Article em En | MEDLINE | ID: mdl-35696549

Assuntos

Dineínas; NF-kappa B; Hepatopatia Gordurosa não Alcoólica; Estresse Oxidativo; Animais; Colina/metabolismo; Dineínas do Citoplasma; Dieta; Modelos Animais de Doenças; Dineínas/genética; Dineínas/metabolismo; Inflamação/metabolismo; Fígado/metabolismo; Fígado/patologia; Metionina/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Inibidor de NF-kappaB alfa/metabolismo; NF-kappa B/metabolismo; Hepatopatia Gordurosa não Alcoólica/genética

Palavras-chave

LC8; NF-κB; inflammation; nonalcoholic steatohepatitis; oxidative stress

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NF-kappa B / Dineínas / Estresse Oxidativo / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Cell Physiol Ano de publicação: 2022 Tipo de documento: Article

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