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PKN2 deficiency leads both to prenatal 'congenital' cardiomyopathy and defective angiotensin II stress responses.
Marshall, Jacqueline J T; Cull, Joshua J; Alharbi, Hajed O; Zaw Thin, May; Cooper, Susanna T E; Barrington, Christopher; Vanyai, Hannah; Snoeks, Thomas; Siow, Bernard; Suáarez-Bonnet, Alejandro; Herbert, Eleanor; Stuckey, Daniel J; Cameron, Angus J M; Prin, Fabrice; Cook, Andrew C; Priestnall, Simon L; Chotani, Sonia; Rackham, Owen J L; Meijles, Daniel N; Mohun, Tim; Clerk, Angela; Parker, Peter J.
Afiliação
  • Marshall JJT; Protein Phosphorylation Laboratory, Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K.
  • Cull JJ; School of Biological Sciences, University of Reading, Reading RG6 2AS, U.K.
  • Alharbi HO; School of Biological Sciences, University of Reading, Reading RG6 2AS, U.K.
  • Zaw Thin M; UCL Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, London WC1E 6DD, U.K.
  • Cooper STE; Molecular and Clinical Sciences Institute, St George's University of London, London SW17 0RE, U.K.
  • Barrington C; Bioinformatics and Biostatistics, Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K.
  • Vanyai H; Epithelial Biology Laboratory, Francis Crick Institute, 1 Midland Road, London London NE1 1AT, U.K.
  • Snoeks T; In Vivo Imaging, Francis Crick Institute, 1 Midland Road, London London NW1 1AT, U.K.
  • Siow B; In Vivo Imaging, Francis Crick Institute, 1 Midland Road, London London NW1 1AT, U.K.
  • Suáarez-Bonnet A; Experimental Histopathology, Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K.
  • Herbert E; Department of Pathobiology & Population Sciences, The Royal Veterinary College, North Mymms, Hatfield, Hertfordshire AL9 7TA, U.K.
  • Stuckey DJ; Experimental Histopathology, Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K.
  • Cameron AJM; Department of Pathobiology & Population Sciences, The Royal Veterinary College, North Mymms, Hatfield, Hertfordshire AL9 7TA, U.K.
  • Prin F; UCL Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, London WC1E 6DD, U.K.
  • Cook AC; Kinase Biology Laboratory, John Vane Science Centre, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, U.K.
  • Priestnall SL; Heart Formation in Vertebrates Laboratory, Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K.
  • Chotani S; Centre for Morphology and Structural Heart Disease, Institute of Institute of Cardiovascular Science, Zayed Centre for Research, 20 Guilford Street, London WC1N 1DZ, U.K.
  • Rackham OJL; Experimental Histopathology, Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K.
  • Meijles DN; Department of Pathobiology & Population Sciences, The Royal Veterinary College, North Mymms, Hatfield, Hertfordshire AL9 7TA, U.K.
  • Mohun T; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, Singapore.
  • Clerk A; Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, Singapore.
  • Parker PJ; Molecular and Clinical Sciences Institute, St George's University of London, London SW17 0RE, U.K.
Biochem J ; 479(13): 1467-1486, 2022 07 15.
Article em En | MEDLINE | ID: mdl-35730579

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Hipertensão / Cardiomiopatias Limite: Animals / Pregnancy Idioma: En Revista: Biochem J Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Hipertensão / Cardiomiopatias Limite: Animals / Pregnancy Idioma: En Revista: Biochem J Ano de publicação: 2022 Tipo de documento: Article