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Oncogenic KRAS G12C: Kinetic and redox characterization of covalent inhibition.
Huynh, Minh V; Parsonage, Derek; Forshaw, Tom E; Chirasani, Venkat R; Hobbs, G Aaron; Wu, Hanzhi; Lee, Jingyun; Furdui, Cristina M; Poole, Leslie B; Campbell, Sharon L.
Afiliação
  • Huynh MV; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Parsonage D; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
  • Forshaw TE; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
  • Chirasani VR; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Hobbs GA; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Wu H; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
  • Lee J; Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina, USA.
  • Furdui CM; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA; Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina, USA; Center for Redox Biology and Medicine, Wake Forest School of Medicine, Winston-Sale
  • Poole LB; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA; Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina, USA; Center for Redox Biology and Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA. Electronic a
  • Campbell SL; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. Electronic address: campbesl@med.unc.edu.
J Biol Chem ; 298(8): 102186, 2022 08.
Article em En | MEDLINE | ID: mdl-35753348
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Sulfidrila / Proteínas Proto-Oncogênicas p21(ras) Tipo de estudo: Prognostic_studies Idioma: En Revista: J Biol Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Sulfidrila / Proteínas Proto-Oncogênicas p21(ras) Tipo de estudo: Prognostic_studies Idioma: En Revista: J Biol Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos