Salmonella phage akira, infecting selected Salmonella enterica Enteritidis and Typhimurium strains, represents a new lineage of bacteriophages.
Arch Virol
; 167(10): 2049-2056, 2022 Oct.
Article
em En
| MEDLINE
| ID: mdl-35764845
ABSTRACT
Some serovars of Salmonella can cause life-threatening diarrhoeal diseases and bacteriemia. The emergence of multidrug-resistant strains has led to a need for alternative treatments such as phage therapy, which requires available, well-described, diverse, and suitable phages. Phage akira was found to lyse 19 out of 32 Salmonella enterica serovars and farm isolates tested, although plaque formation was observed with only two S. Enteritidis and one S. Typhimurium strain. Phage akira encodes anti-defence genes against type 1 R-M systems, is distinct (<65% nucleotide sequence identity) from related phages and has siphovirus morphology. We propose that akira represents a new genus in the class Caudoviricetes.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fagos de Salmonella
/
Bacteriófagos
/
Siphoviridae
/
Salmonella enterica
Idioma:
En
Revista:
Arch Virol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Dinamarca