BDNF Val66Met genotype and adolescent glucocorticoid treatment induce sex-specific disruptions to fear extinction and amygdala GABAergic interneuron expression in mice.

Raju, Sharvada; Notaras, Michael; Grech, Adrienne M; Schroeder, Anna; van den Buuse, Maarten; Hill, Rachel A

Raju, Sharvada; Notaras, Michael; Grech, Adrienne M; Schroeder, Anna; van den Buuse, Maarten; Hill, Rachel A.

Afiliação

Raju S; Behavioural Neuroscience Laboratory, Department of Psychiatry, Monash University, Melbourne, Victoria, Australia.
Notaras M; Behavioural Neuroscience Laboratory, Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia; Centre for Neurogenetics, Feil Family Brain & Mind Research Institute, Weill Cornell Medical College, Cornell University, NY, New York, USA.
Grech AM; Behavioural Neuroscience Laboratory, Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.
Schroeder A; Behavioural Neuroscience Laboratory, Department of Psychiatry, Monash University, Melbourne, Victoria, Australia; Behavioural Neuroscience Laboratory, Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.
van den Buuse M; School of Psychology and Public Health, La Trobe University, Melbourne, Victoria, Australia; Department of Pharmacology, University of Melbourne, Melbourne, Victoria, Australia.
Hill RA; Behavioural Neuroscience Laboratory, Department of Psychiatry, Monash University, Melbourne, Victoria, Australia; Behavioural Neuroscience Laboratory, Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia. Electronic address: Rachel.hill@monash.edu.

Horm Behav ; 144: 105231, 2022 08.

Article em En | MEDLINE | ID: mdl-35779519

Assuntos

Fator Neurotrófico Derivado do Encéfalo; Medo; Tonsila do Cerebelo/metabolismo; Animais; Fator Neurotrófico Derivado do Encéfalo/genética; Fator Neurotrófico Derivado do Encéfalo/metabolismo; Calbindina 2/genética; Calbindina 2/metabolismo; Extinção Psicológica; Feminino; Genótipo; Glucocorticoides/farmacologia; Interneurônios/metabolismo; Masculino; Camundongos; Polimorfismo de Nucleotídeo Único; Somatostatina/genética; Somatostatina/metabolismo

Palavras-chave

Amygdala; Brain-derived neurotrophic factor; Calretinin; Fear extinction; GABAergic interneurons; Post-Traumatic Stress Disorder; Somatostatin; Val66Met

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator Neurotrófico Derivado do Encéfalo / Medo Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Horm Behav Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália

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