Steroidal Antimetabolites Protect Mice against <i>Trypanosoma brucei</i>.

Chaudhuri, Minu; Singha, Ujjal K; Vanderloop, Boden H; Tripathi, Anuj; Nes, W David

Steroidal Antimetabolites Protect Mice against Trypanosoma brucei.

Chaudhuri, Minu; Singha, Ujjal K; Vanderloop, Boden H; Tripathi, Anuj; Nes, W David.

Afiliação

Chaudhuri M; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Singha UK; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Vanderloop BH; Department of Chemistry & Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.
Tripathi A; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Nes WD; Department of Chemistry & Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.

Molecules ; 27(13)2022 Jun 25.

Article em En | MEDLINE | ID: mdl-35807334

Assuntos

Trypanosoma brucei brucei; Tripanossomíase Africana; Animais; Antimetabólitos/metabolismo; Antimetabólitos/farmacologia; Ergosterol; Humanos; Camundongos; Esteroides/farmacologia; Esteróis/metabolismo; Esteróis/farmacologia; Tripanossomíase Africana/tratamento farmacológico; Tripanossomíase Africana/prevenção & controle

Palavras-chave

Trypanosoma brucei; antimetabolite; cholesta-5,7,22,24-tetraenol (CHT); ergosta-5,7,22,24(28)-tetraenol (ERGT); ergosterol biosynthesis; suicide substrate

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trypanosoma brucei brucei / Tripanossomíase Africana Limite: Animals / Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google