18ß-Glycyrrhetinic acid monoglucuronide (GAMG) alleviates single-walled carbon nanotubes (SWCNT)-induced lung inflammation and fibrosis in mice through PI3K/AKT/NF-&#954;B signaling pathway.

Zhang, Xiao-Li; Li, Bo; Zhang, Xiang; Zhu, Jiaojiao; Xie, Yunfeng; Shen, Tong; Tang, Wenjian; Zhang, Jing

18ß-Glycyrrhetinic acid monoglucuronide (GAMG) alleviates single-walled carbon nanotubes (SWCNT)-induced lung inflammation and fibrosis in mice through PI3K/AKT/NF-κB signaling pathway.

Zhang, Xiao-Li; Li, Bo; Zhang, Xiang; Zhu, Jiaojiao; Xie, Yunfeng; Shen, Tong; Tang, Wenjian; Zhang, Jing.

Afiliação

Zhang XL; Department of Occupational Health and Environment Health, School of Public Health, Anhui Medical University, Hefei, China. Electronic address: 1004075487@qq.com.
Li B; Anhui Prevention and Treatment Center for Occupational Disease, Anhui No. 2 Provincial People's Hospital, Hefei 230022, China. Electronic address: lb15209837939@163.com.
Zhang X; Department of Occupational Health and Environment Health, School of Public Health, Anhui Medical University, Hefei, China. Electronic address: 616256518@qq.com.
Zhu J; Department of Occupational Health and Environment Health, School of Public Health, Anhui Medical University, Hefei, China. Electronic address: 975563996@qq.com.
Xie Y; Anhui Prevention and Treatment Center for Occupational Disease, Anhui No. 2 Provincial People's Hospital, Hefei 230022, China. Electronic address: 951763673@qq.com.
Shen T; Department of Occupational Health and Environment Health, School of Public Health, Anhui Medical University, Hefei, China. Electronic address: shentong@ahmu.edu.cn.
Tang W; School of Pharmacy, Anhui Medical University, Hefei 230032, China. Electronic address: ahmupharm@126.com.
Zhang J; Anhui Prevention and Treatment Center for Occupational Disease, Anhui No. 2 Provincial People's Hospital, Hefei 230022, China. Electronic address: hfzj2552@163.com.

Ecotoxicol Environ Saf ; 242: 113858, 2022 Sep 01.

Article em En | MEDLINE | ID: mdl-35809393

Assuntos

Ácido Glicirretínico; Nanotubos de Carbono; Pneumonia; Fibrose Pulmonar; Animais; Colágeno/metabolismo; Fibrose; Ácido Glicirretínico/análogos & derivados; Ácido Glicirretínico/metabolismo; Ácido Glicirretínico/toxicidade; Pulmão/metabolismo; Camundongos; NF-kappa B/metabolismo; Nanotubos de Carbono/toxicidade; Fosfatidilinositol 3-Quinases/metabolismo; Pneumonia/patologia; Proteínas Proto-Oncogênicas c-akt/metabolismo; Fibrose Pulmonar/induzido quimicamente; Fibrose Pulmonar/tratamento farmacológico; Fibrose Pulmonar/patologia; Transdução de Sinais

Palavras-chave

Glycyrrhizic acid 3-O-mono-ß-D-glucuronide (GAMG); Glycyrrhizin; Inflammation; Pulmonary fibrosis; Signaling pathway; Single-walled carbon nanotubes (SWCNT)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia / Fibrose Pulmonar / Nanotubos de Carbono / Ácido Glicirretínico Limite: Animals Idioma: En Revista: Ecotoxicol Environ Saf Ano de publicação: 2022 Tipo de documento: Article

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