COVID-19 vaccination-triggered cluster headache episodes with frequent attacks.
Cephalalgia
; 42(13): 1420-1424, 2022 11.
Article
em En
| MEDLINE
| ID: mdl-35833226
ABSTRACT
BACKGROUND:
The pathophysiology of cluster headache and how cluster episodes are triggered, are still poorly understood. Recurrent inflammation of the trigeminovascular system has been hypothesized. It was noted that some long-term attack-free cluster headache patients suddenly developed a new cluster episode shortly after COVID-19 vaccination.METHODS:
Cases are described from patients with cluster headache who reported a new cluster episode within days after COVID-19 vaccination. All cases were seen in a tertiary university referral center and a general hospital in the Netherlands between March 2021 and December 2021, when the first COVID-19 vaccinations were carried out in The Netherlands. Clinical characteristics of the previous and new cluster episodes, and time between the onset of a new cluster episode and a previous COVID-19 vaccination were reported.RESULTS:
We report seven patients with cluster headache, who had been attack-free for a long time, in whom a new cluster episode occurred within a few days after a COVID-19 vaccination.INTERPRETATION:
COVID-19 vaccinations may trigger new cluster episodes in patients with cluster headache, possibly by activating a pro-inflammatory state of the trigeminocervical complex. COVID-19 vaccinations may also exacerbate other neuroinflammatory conditions. .Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cefaleia Histamínica
/
Vacinas contra COVID-19
/
COVID-19
Tipo de estudo:
Etiology_studies
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Cephalalgia
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Holanda