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Dementia prevention: The potential long-term cost-effectiveness of the FINGER prevention program.
Wimo, Anders; Handels, Ron; Antikainen, Riitta; Eriksdotter, Maria; Jönsson, Linus; Knapp, Martin; Kulmala, Jenni; Laatikainen, Tiina; Lehtisalo, Jenni; Peltonen, Markku; Sköldunger, Anders; Soininen, Hilkka; Solomon, Alina; Strandberg, Timo; Tuomilehto, Jaakko; Ngandu, Tiia; Kivipelto, Miia.
Afiliação
  • Wimo A; Department of NVS, Centre of Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.
  • Handels R; Department of NVS, Centre of Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.
  • Antikainen R; Deperatment of Psychiatry and Neuropsychology, Maastricht University, Alzheimer Centre Limburg, School for Mental Health and Neurosciences, Maastricht, the Netherlands.
  • Eriksdotter M; Center for Life Course Health Research/Geriatrics, University of Oulu, Medical Research Center, Oulu University Hospital, Oulu, Finland.
  • Jönsson L; Department of NVS, Centre of Alzheimer Research, Division of Clinical Geriatrics Karolinska Institutet, Stockholm, Sweden.
  • Knapp M; Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden.
  • Kulmala J; Department of NVS, Centre of Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden.
  • Laatikainen T; Care Policy and Evaluation Centre, Department of Health Policy, London School of Economics and Political Science, London, UK.
  • Lehtisalo J; Faculty of Social Sciences (Health Sciences) and Gerontology Research Center (GEREC), Tampere University, Tampere, Finland.
  • Peltonen M; Division of Clinical Geriatrics, Center for Alzheimer Research, NVS, Karolinska Institutet, Stockholm, Sweden.
  • Sköldunger A; Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.
  • Soininen H; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.
  • Solomon A; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
  • Strandberg T; Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.
  • Tuomilehto J; Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.
  • Ngandu T; Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.
  • Kivipelto M; Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Alzheimers Dement ; 2022 Jul 16.
Article em En | MEDLINE | ID: mdl-35841619
ABSTRACT

INTRODUCTION:

The aim of this study was to estimate the potential cost-effectiveness of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) program.

METHODS:

A life-time Markov model with societal perspective, simulating a cohort of people at risk of dementia reflecting usual care and the FINGER program.

RESULTS:

Costs were 1,653,275 and 1,635,346 SEK and quality-adjusted life years (QALYs) were 8.636 and 8.679 for usual care and the FINGER program, respectively, resulting in savings of 16,928 SEK (2023 US$) and 0.043 QALY gains per person, supporting extended dominance for the FINGER program. A total of 1623 dementia cases were avoided with 0.17 fewer person-years living with dementia. The sensitivity analysis confirmed the conclusions in most scenarios.

DISCUSSION:

The model provides support that programs like FINGER have the potential to be cost-effective in preventing dementia. Results at the individual level are rather modest, but the societal benefits can be substantial because of the large potential target population.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Evaluation_studies / Health_economic_evaluation Idioma: En Revista: Alzheimers Dement Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suécia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Evaluation_studies / Health_economic_evaluation Idioma: En Revista: Alzheimers Dement Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suécia