Morphine ameliorates pentylenetetrazole-induced locomotor pattern in zebrafish embryos; mechanism involving regulation of opioid receptors, suppression of oxidative stress, and inflammation in epileptogenesis.

Üstündag, Fümet Duygu; Ünal, Ismail; Üstündag, Ünsal Veli; Cansiz, Derya; Beler, Merih; Alturfan, A Ata; Tiber, Pinar Mega; Emekli-Alturfan, Ebru

Üstündag, Fümet Duygu; Ünal, Ismail; Üstündag, Ünsal Veli; Cansiz, Derya; Beler, Merih; Alturfan, A Ata; Tiber, Pinar Mega; Emekli-Alturfan, Ebru.

Afiliação

Üstündag FD; Department of Biophysics, Institute of Health Sciences, Marmara University, Istanbul, Turkey.
Ünal I; Department of Biochemistry, Institute of Health Sciences, Marmara University, Istanbul, Turkey.
Üstündag ÜV; Faculty of Medicine, Medical Biochemistry, Istanbul Medipol University, Istanbul, Turkey.
Cansiz D; Faculty of Medicine, Medical Biochemistry, Istanbul Medipol University, Istanbul, Turkey.
Beler M; Department of Biochemistry, Institute of Health Sciences, Marmara University, Istanbul, Turkey.
Alturfan AA; Department of Biochemistry, Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Tiber PM; Department of Biophysics, Faculty of Medicine, Marmara University, Istanbul, Turkey.
Emekli-Alturfan E; Department of Basic Medical Sciences, Faculty of Dentistry, Marmara University, Istanbul, Turkey.

Toxicol Mech Methods ; 33(2): 151-160, 2023 Feb.

Article em En | MEDLINE | ID: mdl-35866229

Assuntos

Epilepsia; Morfina; Pentilenotetrazol; Animais; Acetilcolinesterase; Anticonvulsivantes/uso terapêutico; Antioxidantes/metabolismo; Fator Neurotrófico Derivado do Encéfalo; Epilepsia/induzido quimicamente; Epilepsia/tratamento farmacológico; Inflamação; Morfina/uso terapêutico; Estresse Oxidativo; Pentilenotetrazol/toxicidade; Receptores Opioides/genética; Convulsões/induzido quimicamente; Convulsões/tratamento farmacológico; Ácido Valproico/uso terapêutico; Peixe-Zebra

Palavras-chave

Pentylenetetrazole; morphine; oxidant-antioxidant; valproic acid; zebrafish embryos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pentilenotetrazol / Epilepsia / Morfina Limite: Animals Idioma: En Revista: Toxicol Mech Methods Assunto da revista: TOXICOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Turquia

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