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The term CAKUT has outlived its usefulness: the case for the defense.
Knoers, Nine V A M.
Afiliação
  • Knoers NVAM; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands. v.v.a.m.knoers@umcg.nl.
Pediatr Nephrol ; 37(11): 2793-2798, 2022 11.
Article em En | MEDLINE | ID: mdl-35867161
Congenital anomalies of the kidney and urinary tract form a spectrum of congenital structural disorders that are generally known under the term CAKUT. The term CAKUT was introduced 20 years ago and has been used extensively in literature since. Prof. Woolf has made a plea for abandoning this term in his "case for the prosecution." Here, I advocate for the continued use of CAKUT as an umbrella term for these related congenital kidney and urinary tract abnormalities. I explain why the term CAKUT accurately and usefully defines this group of related structural disorders with prenatal origin and why it makes sense to continue grouping these disorders given accumulating evidence for shared etiology of CAKUT phenotypes and the importance of grouping CAKUT phenotypes in genetic counseling.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Urinário / Anormalidades Urogenitais / Refluxo Vesicoureteral Limite: Female / Humans / Pregnancy Idioma: En Revista: Pediatr Nephrol Assunto da revista: NEFROLOGIA / PEDIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Urinário / Anormalidades Urogenitais / Refluxo Vesicoureteral Limite: Female / Humans / Pregnancy Idioma: En Revista: Pediatr Nephrol Assunto da revista: NEFROLOGIA / PEDIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda