Inhibition of SHMT2 mRNA translation increases embryonic mortality in sheep.

Sah, Nirvay; Stenhouse, Claire; Halloran, Katherine M; Moses, Robyn M; Seo, Heewon; Burghardt, Robert C; Johnson, Gregory A; Wu, Guoyao; Bazer, Fuller W

Inhibition of SHMT2 mRNA translation increases embryonic mortality in sheep.

Sah, Nirvay; Stenhouse, Claire; Halloran, Katherine M; Moses, Robyn M; Seo, Heewon; Burghardt, Robert C; Johnson, Gregory A; Wu, Guoyao; Bazer, Fuller W.

Afiliação

Sah N; Department of Animal Science, Texas A&M University, College Station, TX, USA.
Stenhouse C; Department of Animal Science, Texas A&M University, College Station, TX, USA.
Halloran KM; Department of Animal Science, Texas A&M University, College Station, TX, USA.
Moses RM; Department of Animal Science, Texas A&M University, College Station, TX, USA.
Seo H; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, College Station, TX, USA.
Burghardt RC; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, College Station, TX, USA.
Johnson GA; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, College Station, TX, USA.
Wu G; Department of Animal Science, Texas A&M University, College Station, TX, USA.
Bazer FW; Department of Animal Science, Texas A&M University, College Station, TX, USA.

Biol Reprod ; 107(5): 1279-1295, 2022 11 14.

Article em En | MEDLINE | ID: mdl-35871545

Assuntos

Implantação do Embrião; Epigênese Genética; Gravidez; Ovinos; Animais; Feminino; Implantação do Embrião/fisiologia; Biossíntese de Proteínas; Embrião de Mamíferos/metabolismo; Oligonucleotídeos Antissenso/metabolismo; Oligonucleotídeos Antissenso/farmacologia; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Monoaminoxidase/genética; Monoaminoxidase/metabolismo; Monoaminoxidase/farmacologia

Palavras-chave

SHMT2; conceptus; one-carbon metabolism; ovine trophectoderm cell; sheep

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Implantação do Embrião / Epigênese Genética Limite: Animals / Pregnancy Idioma: En Revista: Biol Reprod Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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