8-Hydroxy-1,6-naphthyridine-7-carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease.

Jung, Eunkyung; Majima, Ryuichi; Edwards, Tiffany C; Soto-Acosta, Ruben; Geraghty, Robert J; Wang, Zhengqiang

Jung, Eunkyung; Majima, Ryuichi; Edwards, Tiffany C; Soto-Acosta, Ruben; Geraghty, Robert J; Wang, Zhengqiang.

Afiliação

Jung E; Center for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Majima R; Center for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Edwards TC; Center for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Soto-Acosta R; Center for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Geraghty RJ; Center for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Wang Z; Center for Drug Design, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.

ChemMedChem ; 17(17): e202200334, 2022 09 05.

Article em En | MEDLINE | ID: mdl-35879245

Assuntos

Amidas/farmacologia; Citomegalovirus; Endonucleases; Antivirais/química; Antivirais/farmacologia; Endodesoxirribonucleases/química; Humanos; Simulação de Acoplamento Molecular; Naftiridinas/farmacologia; Proteínas Virais/química

Palavras-chave

8-hydroxy-1,6-naphthyridine-7-carboxamide; endonuclease; human cytomegalovirus; inhibitor; pUL89-C

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citomegalovirus / Endonucleases / Amidas Limite: Humans Idioma: En Revista: ChemMedChem Assunto da revista: FARMACOLOGIA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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