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Exploring Contemporary Data on Lipid-Lowering Therapy Prescribing in Patients Following Discharge for Atherosclerotic Cardiovascular Disease in the South of Italy.
Citarella, Anna; Cammarota, Simona; Bernardi, Francesca Futura; Caliendo, Luigi; D'Andrea, Antonello; Fimiani, Biagio; Fogliasecca, Marianna; Pacella, Daniela; Pagnotta, Rita; Trama, Ugo; Zito, Giovanni Battista; Cillo, Mariarosaria; Vercellone, Adriano.
Afiliação
  • Citarella A; LinkHealth Health Economics, Outcomes & Epidemiology S.R.L., 80143 Naples, Italy.
  • Cammarota S; LinkHealth Health Economics, Outcomes & Epidemiology S.R.L., 80143 Naples, Italy.
  • Bernardi FF; Regional Pharmaceutical Unit, Campania Region, 80143 Naples, Italy.
  • Caliendo L; Department of Cardiology, Santa Maria della Pietà Hospital, Nola, 80035 Naples, Italy.
  • D'Andrea A; Department of Cardiology and Intensive Care Unit, Umberto I Hospital, Nocera Inferiore, 84014 Salerno, Italy.
  • Fimiani B; Cardiology Service, Local Health Unit (LHU) Salerno, Associazioni Regionali Cardiologi Ambulatoriali (ARCA), 84129 Salerno, Italy.
  • Fogliasecca M; LinkHealth Health Economics, Outcomes & Epidemiology S.R.L., 80143 Naples, Italy.
  • Pacella D; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
  • Pagnotta R; Department of Management Control, Local Health Unit (LHU) Naples 3 South, 80053 Naples, Italy.
  • Trama U; Regional Pharmaceutical Unit, Campania Region, 80143 Naples, Italy.
  • Zito GB; Cardiology Service, Local Health Unit (LHU) Naples 3 South, Associazioni Regionali Cardiologi Ambulatoriali (ARCA), 80045 Naples, Italy.
  • Cillo M; Pharmaceutical Department, Local Health Unit (LHU) Salerno, 84124 Salerno, Italy.
  • Vercellone A; Pharmaceutical Department, Local Health Unit (LHU) Naples 3 South, 80053 Naples, Italy.
J Clin Med ; 11(15)2022 Jul 26.
Article em En | MEDLINE | ID: mdl-35893434
Current international guidelines strongly recommend the use of high-intensity lipid-lowering therapy (LLT) after hospitalization for atherosclerotic cardiovascular disease (ASCVD) events. With this study, our aim was to evaluate LLT prescribing in a large Italian cohort of patients after discharge for an ASCVD event, exploring factors associated with a lower likelihood of receiving any LLT and high-intensity LLT. Individuals aged 18 years and older discharged for an ASCVD event in 2019-2020 were identified using hospital discharge abstracts from two local health units of the Campania region. LLT treatment patterns were analyzed in the 6 months after the index event. Logistic regression models were developed for estimating patient predictors of any LLT prescription and to compare high-intensity and low-to-moderate-intensity LLT. Results: A total of 8705 subjects were identified. In the 6 months post-discharge, 56.7% of patients were prescribed LLT and, of those, 48.7% were high-intensity LLT. Female sex, older age, and stroke/TIA or PAD conditions were associated with a higher likelihood of not receiving high-intensity LLT. Similar predictors were found for LLT prescriptions. LLT utilization and the specific use of high-intensity LLT remain low in patients with ASCVD, suggesting a substantial unmet need among these patients in the contemporary real-world setting.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline / Prognostic_studies Idioma: En Revista: J Clin Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline / Prognostic_studies Idioma: En Revista: J Clin Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália