Systems metabolic engineering of Corynebacterium glutamicum eliminates all by-products for selective and high-yield production of the platform chemical 5-aminovalerate.

Rohles, Christina; Pauli, Sarah; Gießelmann, Gideon; Kohlstedt, Michael; Becker, Judith; Wittmann, Christoph

Rohles, Christina; Pauli, Sarah; Gießelmann, Gideon; Kohlstedt, Michael; Becker, Judith; Wittmann, Christoph.

Afiliação

Rohles C; Institute of Systems Biotechnology, Saarland University, Germany.
Pauli S; Institute of Systems Biotechnology, Saarland University, Germany.
Gießelmann G; Institute of Systems Biotechnology, Saarland University, Germany.
Kohlstedt M; Institute of Systems Biotechnology, Saarland University, Germany.
Becker J; Institute of Systems Biotechnology, Saarland University, Germany.
Wittmann C; Institute of Systems Biotechnology, Saarland University, Germany. Electronic address: christoph.wittmann@uni-saarland.de.

Metab Eng ; 73: 168-181, 2022 09.

Article em En | MEDLINE | ID: mdl-35917915

Assuntos

Corynebacterium glutamicum; Carbono/metabolismo; Corynebacterium glutamicum/genética; Corynebacterium glutamicum/metabolismo; Fermentação; Glutaratos/metabolismo; Proteínas de Membrana Transportadoras/genética; Engenharia Metabólica

Palavras-chave

Arginine; Bioeconomy; Corynebacterium glutamicum; Export; Fed-batch; GABA permease; Glutarate; Import; Lysine; Pseudomonas putida KT2440; Systems metabolic engineering

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Corynebacterium glutamicum Idioma: En Revista: Metab Eng Assunto da revista: ENGENHARIA BIOMEDICA / METABOLISMO Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha

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