Prevalence rates of chronic kidney disease and its association with cardiometabolic factors and cardiovascular diseases. SIMETAP-CKD study. / Tasas de prevalencia de enfermedad renal crónica y su asociación con factores cardiometabólicos y enfermedades cardiovasculares. Estudio SIMETAP-ERC.
Clin Investig Arterioscler
; 35(2): 64-74, 2023.
Article
em En, Es
| MEDLINE
| ID: mdl-35945036
ABSTRACT
INTRODUCTION:
Chronic kidney disease (CKD) is a major health problem that contributes to the development of cardiovascular disorders such as heart failure and arteriosclerotic cardiovascular disease (ACVD). The aims of this study were to determine the prevalence of CKD and to assess its association with ACVD and cardiometabolic risk factors.METHODS:
Cross-sectional observational study conducted in primary care setting. Population-based random sample 6,588 people between 18 and 102 years old (response rate 66%). Crude and sex- and age-adjusted prevalence rates of CKD according to KDIGO were determined by assessing albuminuria and estimated glomerular filtration rate according to CKD-EPI, and their associations with cardiometabolic factors and ACVD were determined.RESULTS:
The crude prevalence of CKD was 11.48% (95%CI 10.72-12.27%), without significant difference between men (11.64% [95%CI 10.49-12.86%]) and women (11.35% [95%CI 10.34-12.41%]). The age- and sex-adjusted prevalence rate of CKD was 9.16% (men 8.61%; women 9.69%). The prevalence of low estimated glomerular filtration rate (<60mL/min/1.73m2) and albuminuria (≥30mg/g) were 7.95% (95%CI 7.30-8.61) and 5.98% (95%CI 5.41-6.55), respectively. Hypertension, diabetes, prediabetes, increased waist-to-height ratio, heart failure, atrial fibrillation, and ACVD were independently associated with CKD (P<.001). Very high cardiovascular risk according to SCORE was found in 77.51% (95%CI 74.54-80.49) of the population with CKD.CONCLUSIONS:
The adjusted prevalence of CKD was 9.2% (low estimated glomerular filtration rate 8.0%; albuminuria 6.0%). Most of the patients with CKD had very high cardiovascular risk. Hypertension, diabetes, prediabetes, increased waist-to-height ratio and ACVD were independently associated with CKD.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estado Pré-Diabético
/
Doenças Cardiovasculares
/
Diabetes Mellitus
/
Insuficiência Renal Crônica
/
Insuficiência Cardíaca
/
Hipertensão
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
/
Es
Revista:
Clin Investig Arterioscler
Ano de publicação:
2023
Tipo de documento:
Article