Ion channel model reduction using manifold boundaries.

Whittaker, Dominic G; Wang, Jiahui; Shuttleworth, Joseph G; Venkateshappa, Ravichandra; Kemp, Jacob M; Claydon, Thomas W; Mirams, Gary R

Whittaker, Dominic G; Wang, Jiahui; Shuttleworth, Joseph G; Venkateshappa, Ravichandra; Kemp, Jacob M; Claydon, Thomas W; Mirams, Gary R.

Afiliação

Whittaker DG; Centre for Mathematical Medicine and Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, UK.
Wang J; Centre for Mathematical Medicine and Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, UK.
Shuttleworth JG; Centre for Mathematical Medicine and Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, UK.
Venkateshappa R; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, Canada.
Kemp JM; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, Canada.
Claydon TW; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, Canada.
Mirams GR; Centre for Mathematical Medicine and Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, UK.

J R Soc Interface ; 19(193): 20220193, 2022 08.

Article em En | MEDLINE | ID: mdl-35946166

Assuntos

Canais de Potássio Éter-A-Go-Go; Canais Iônicos; Canal de Potássio ERG1/genética; Células HEK293; Coração; Humanos

Palavras-chave

electrophysiology; identifiability; ion channel; mathematical model; model reduction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canais de Potássio Éter-A-Go-Go / Canais Iônicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J R Soc Interface Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

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