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A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age-dependent differences in absorption.
Streekstra, Eva J; Kiss, Márton; van den Heuvel, Jeroen; Nicolaï, Johan; van den Broek, Petra; Botden, Sanne M B I; Stommel, Martijn W J; van Rijssel, Lara; Ungell, Anna-Lena; van de Steeg, Evita; Russel, Frans G M; de Wildt, Saskia N.
Afiliação
  • Streekstra EJ; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Kiss M; Department of Metabolic Health Research, TNO, Zeist, The Netherlands.
  • van den Heuvel J; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Nicolaï J; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • van den Broek P; Development Science, UCB Biopharma SRL, Braine-l'Alleud, Belgium.
  • Botden SMBI; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Stommel MWJ; Department of Pediatric Surgery, Radboudumc-Amalia Children's Hospital, Nijmegen, The Netherlands.
  • van Rijssel L; Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Ungell AL; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • van de Steeg E; Development Science, UCB Biopharma SRL, Braine-l'Alleud, Belgium.
  • Russel FGM; Department of Metabolic Health Research, TNO, Zeist, The Netherlands.
  • de Wildt SN; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.
Clin Transl Sci ; 15(10): 2392-2402, 2022 10.
Article em En | MEDLINE | ID: mdl-35962572
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propranolol / Mucosa Intestinal Limite: Adolescent / Child / Child, preschool / Humans / Infant Idioma: En Revista: Clin Transl Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propranolol / Mucosa Intestinal Limite: Adolescent / Child / Child, preschool / Humans / Infant Idioma: En Revista: Clin Transl Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda