Immune Responses and Immunosuppressive Strategies for Adeno-Associated Virus-Based Gene Therapy for Treatment of Central Nervous System Disorders: Current Knowledge and Approaches.

Prasad, Suyash; Dimmock, David P; Greenberg, Benjamin; Walia, Jagdeep S; Sadhu, Chanchal; Tavakkoli, Fatemeh; Lipshutz, Gerald S

Prasad, Suyash; Dimmock, David P; Greenberg, Benjamin; Walia, Jagdeep S; Sadhu, Chanchal; Tavakkoli, Fatemeh; Lipshutz, Gerald S.

Afiliação

Prasad S; Taysha Gene Therapies, Dallas, Texas, USA.
Dimmock DP; Rady Children's Institute for Genomic Medicine, Rady Children's Hospital, San Diego, California, USA.
Greenberg B; Department of Neurology, O'Donnell Brain Institute, University of Texas Southwestern, Dallas, Texas, USA.
Walia JS; Division of Medical Genetics, Department of Pediatrics, Queen's University, Kingston, Canada.
Sadhu C; Taysha Gene Therapies, Dallas, Texas, USA.
Tavakkoli F; Taysha Gene Therapies, Dallas, Texas, USA.
Lipshutz GS; Departments of Molecular and Medical Pharmacology and Surgery, Intellectual and Developmental Disabilities Research Center at UCLA, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

Hum Gene Ther ; 33(23-24): 1228-1245, 2022 12.

Article em En | MEDLINE | ID: mdl-35994385

Assuntos

Doenças do Sistema Nervoso Central; Dependovirus; Humanos; Dependovirus/genética; Vetores Genéticos/genética; Vetores Genéticos/uso terapêutico; Terapia Genética; Imunidade Humoral; Imunossupressores; Doenças do Sistema Nervoso Central/genética; Doenças do Sistema Nervoso Central/terapia

Palavras-chave

CNS; adaptive immunity; adeno-associated virus; gene therapy; immunosuppression; innate immunity

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças do Sistema Nervoso Central / Dependovirus Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Hum Gene Ther Assunto da revista: GENETICA MEDICA / TERAPEUTICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google