Identification of a Dual Inhibitor of Secreted Phospholipase A<sub>2</sub> (GIIA sPLA<sub>2</sub>) and SARS-CoV-2 Main Protease.

Theodoropoulou, Maria A; Koutoulogenis, Giorgos S; Zhang, Linlin; Akrani, Ifigeneia; Mikros, Emmanuel; Hilgenfeld, Rolf; Kokotos, George

Identification of a Dual Inhibitor of Secreted Phospholipase A₂ (GIIA sPLA₂) and SARS-CoV-2 Main Protease.

Theodoropoulou, Maria A; Koutoulogenis, Giorgos S; Zhang, Linlin; Akrani, Ifigeneia; Mikros, Emmanuel; Hilgenfeld, Rolf; Kokotos, George.

Afiliação

Theodoropoulou MA; Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Athens, Greece.
Koutoulogenis GS; Center of Excellence for Drug Design and Discovery, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Zhang L; Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Athens, Greece.
Akrani I; Center of Excellence for Drug Design and Discovery, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Mikros E; Institute of Molecular Medicine, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.
Hilgenfeld R; Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Athens, Greece.
Kokotos G; Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Athens, Greece.

Pharmaceuticals (Basel) ; 15(8)2022 Aug 03.

Article em En | MEDLINE | ID: mdl-36015109

Palavras-chave

2-oxoamides; COVID-19; SARS-CoV-2; inhibitors; main protease; phospholipase A2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Pharmaceuticals (Basel) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Grécia

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