Serotonin 5-HT2A, 5-HT2c and 5-HT1A receptor involvement in the acute effects of psilocybin in mice. In vitro pharmacological profile and modulation of thermoregulation and head-twich response.

Erkizia-Santamaría, I; Alles-Pascual, R; Horrillo, I; Meana, J J; Ortega, J E

Serotonin 5-HT_2A, 5-HT_2c and 5-HT_1A receptor involvement in the acute effects of psilocybin in mice. In vitro pharmacological profile and modulation of thermoregulation and head-twich response.

Erkizia-Santamaría, I; Alles-Pascual, R; Horrillo, I; Meana, J J; Ortega, J E.

Afiliação

Erkizia-Santamaría I; Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain.
Alles-Pascual R; Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain.
Horrillo I; Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain; Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, Spain; Biocruces Bizkaia Health Research Institute, Barakaldo, Bizkaia, Spain.
Meana JJ; Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain; Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, Spain; Biocruces Bizkaia Health Research Institute, Barakaldo, Bizkaia, Spain.
Ortega JE; Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain; Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, Spain; Biocruces Bizkaia Health Research Institute, Barakaldo, Bizkaia, Spain. Electronic address: jorge.ortega@ehu.eu

Biomed Pharmacother ; 154: 113612, 2022 Oct.

Article em En | MEDLINE | ID: mdl-36049313

Assuntos

Alucinógenos; Psilocibina; Animais; Regulação da Temperatura Corporal; Alucinógenos/farmacologia; Humanos; Camundongos; Psilocibina/farmacologia; Receptor 5-HT1A de Serotonina; Serotonina

Palavras-chave

5-HT(1A) receptors; 5-HT(2A) receptors; 5-HT(2C) receptors; Body temperature; Head-twitch response; Psilocybin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psilocibina / Alucinógenos Limite: Animals / Humans Idioma: En Revista: Biomed Pharmacother Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Espanha

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