Pre-exposure to mRNA-LNP inhibits adaptive immune responses and alters innate immune fitness in an inheritable fashion.

Qin, Zhen; Bouteau, Aurélie; Herbst, Christopher; Igyártó, Botond Z

Qin, Zhen; Bouteau, Aurélie; Herbst, Christopher; Igyártó, Botond Z.

Afiliação

Qin Z; Department of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.
Bouteau A; Department of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.
Herbst C; Department of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.
Igyártó BZ; Department of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.

PLoS Pathog ; 18(9): e1010830, 2022 09.

Article em En | MEDLINE | ID: mdl-36054264

Assuntos

COVID-19; Nanopartículas; Animais; COVID-19/prevenção & controle; Vacinas contra COVID-19; Humanos; Imunidade Humoral; Imunidade Inata; Inflamação; Lipídeos; Camundongos; RNA Mensageiro/genética; SARS-CoV-2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas / COVID-19 Limite: Animals / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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