The prevalence and prognosis of minimally elevated creatine kinase-myocardial band activity in elderly patients with syncope.
Arch Intern Med
; 147(7): 1321-3, 1987 Jul.
Article
em En
| MEDLINE
| ID: mdl-3606288
ABSTRACT
Syncope in elderly patients is often the initial manifestation of myocardial infarction (MI). Small elevations in creatine kinase-myocardial band (CK-MB) activity following syncope may represent MI, transient myocardial hypoperfusion, or insignificant background activity. To determine the prevalence and prognostic significance of minimal CK-MB elevations in elderly patients with syncope, serial serum CK-MB activities and subsequent survival experiences were determined for elderly syncope patients with and without MI, and for age-matched nonsyncopal controls. While all syncope patients with MI by specific clinical criteria had one or more abnormal CK-MB levels (greater than 5 U/L) and died within 31 months, 10% of syncope patients without MI and 10% of controls had abnormal CK-MB with no impact on mortality. Using standard clinical laboratory techniques, minimal elevation in CK-MB was found in 10% of elderly subjects with and without syncope and probably had no prognostic significance.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síncope
/
Creatina Quinase
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Humans
Idioma:
En
Revista:
Arch Intern Med
Ano de publicação:
1987
Tipo de documento:
Article