RNA structure-altering mutations underlying positive selection on Spike protein reveal novel putative signatures to trace crossing host-species barriers in <i>Betacoronavirus</i>.

Rojas-Cruz, Alexis Felipe; Gallego-Gómez, Juan Carlos; Bermúdez-Santana, Clara Isabel

RNA structure-altering mutations underlying positive selection on Spike protein reveal novel putative signatures to trace crossing host-species barriers in Betacoronavirus.

Rojas-Cruz, Alexis Felipe; Gallego-Gómez, Juan Carlos; Bermúdez-Santana, Clara Isabel.

Afiliação

Rojas-Cruz AF; Theoretical and Computational RNomics Group, Department of Biology, Faculty of Sciences, National University of Colombia, Bogota Colombia.
Gallego-Gómez JC; Molecular and Translational Medicine Group, Faculty of Medicine, University of Antioquia, Medellin Colombia.
Bermúdez-Santana CI; Theoretical and Computational RNomics Group, Department of Biology, Faculty of Sciences, National University of Colombia, Bogota Colombia.

RNA Biol ; 19(1): 1019-1044, 2022 01.

Article em En | MEDLINE | ID: mdl-36102368

Assuntos

COVID-19; Quirópteros; Animais; COVID-19/genética; Quirópteros/genética; Humanos; Mutação; Filogenia; RNA; SARS-CoV-2/genética; Glicoproteína da Espícula de Coronavírus/genética; Proteínas Virais

Palavras-chave

Betacoronavirus; cross-species horizontal transmission; jumping the species barrier; molecular evolution; natural selection; secondary RNA structures; viral RNA genome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quirópteros / COVID-19 Tipo de estudo: Qualitative_research Limite: Animals / Humans Idioma: En Revista: RNA Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article

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