Treatment with Amniotic Fluid Stem Cell Extracellular Vesicles Promotes Fetal Lung Branching and Cell Differentiation at Canalicular and Saccular Stages in Experimental Pulmonary Hypoplasia Secondary to Congenital Diaphragmatic Hernia.

Khalaj, Kasra; Figueira, Rebeca Lopes; Antounians, Lina; Gandhi, Sree; Wales, Matthew; Montalva, Louise; Biouss, George; Zani, Augusto

Khalaj, Kasra; Figueira, Rebeca Lopes; Antounians, Lina; Gandhi, Sree; Wales, Matthew; Montalva, Louise; Biouss, George; Zani, Augusto.

Afiliação

Khalaj K; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
Figueira RL; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Antounians L; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
Gandhi S; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Wales M; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
Montalva L; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Biouss G; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
Zani A; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.

Stem Cells Transl Med ; 11(10): 1089-1102, 2022 Oct 21.

Article em En | MEDLINE | ID: mdl-36103370

Assuntos

Vesículas Extracelulares; Hérnias Diafragmáticas Congênitas; MicroRNAs; Ratos; Animais; Hérnias Diafragmáticas Congênitas/metabolismo; beta Catenina/metabolismo; Líquido Amniótico/metabolismo; Neuropilina-1/metabolismo; Ratos Sprague-Dawley; Pulmão/metabolismo; Células-Tronco/metabolismo; Diferenciação Celular; RNA Mensageiro/metabolismo; Vesículas Extracelulares/metabolismo; MicroRNAs/metabolismo; Efrinas/metabolismo; Modelos Animais de Doenças

Palavras-chave

congenital diaphragmatic hernia; exosome; extracellular vesicles; fetal medicine; lung development; microRNA; pulmonary hypoplasia; regenerative medicine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Hérnias Diafragmáticas Congênitas / Vesículas Extracelulares Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Stem Cells Transl Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá

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