Heat Shock Protein 60 Is Involved in Viral Replication Complex Formation and Facilitates Foot and Mouth Virus Replication by Stabilizing Viral Nonstructural Proteins 3A and 2C.

Tang, Jianli; Abdullah, Sahibzada Waheed; Li, Pinghua; Wu, Jin'en; Pei, Chenchen; Mu, Suyu; Wang, Yunlu; Sun, Shiqi; Guo, Huichen

Tang, Jianli; Abdullah, Sahibzada Waheed; Li, Pinghua; Wu, Jin'en; Pei, Chenchen; Mu, Suyu; Wang, Yunlu; Sun, Shiqi; Guo, Huichen.

Afiliação

Tang J; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Abdullah SW; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Li P; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Wu J; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Pei C; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Mu S; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Wang Y; College of Animal Science, University of Tibet Agricultural and Animal Husbandry, Linzhi, Tibet, China.
Sun S; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.
Guo H; State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China.

mBio ; 13(5): e0143422, 2022 10 26.

Article em En | MEDLINE | ID: mdl-36106732

Assuntos

Vírus da Febre Aftosa; Febre Aftosa; Animais; Camundongos; Proteínas não Estruturais Virais/genética; Proteínas não Estruturais Virais/metabolismo; Chaperonina 60/metabolismo; RNA Viral/genética; RNA Viral/metabolismo; RNA Interferente Pequeno/metabolismo; Linhagem Celular; Vírus da Febre Aftosa/genética; Replicação Viral/fisiologia; Antivirais/metabolismo; Caspases/metabolismo

Palavras-chave

2C; 3A; FMDV; HSP60; replication complex

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Febre Aftosa / Febre Aftosa Limite: Animals Idioma: En Revista: MBio Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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