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Structures of α-synuclein filaments from human brains with Lewy pathology.
Yang, Yang; Shi, Yang; Schweighauser, Manuel; Zhang, Xianjun; Kotecha, Abhay; Murzin, Alexey G; Garringer, Holly J; Cullinane, Patrick W; Saito, Yuko; Foroud, Tatiana; Warner, Thomas T; Hasegawa, Kazuko; Vidal, Ruben; Murayama, Shigeo; Revesz, Tamas; Ghetti, Bernardino; Hasegawa, Masato; Lashley, Tammaryn; Scheres, Sjors H W; Goedert, Michel.
Afiliação
  • Yang Y; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.
  • Shi Y; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.
  • Schweighauser M; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.
  • Zhang X; Thermo Fisher Scientific, Eindhoven, The Netherlands.
  • Kotecha A; Thermo Fisher Scientific, Eindhoven, The Netherlands.
  • Murzin AG; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.
  • Garringer HJ; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Cullinane PW; Department of Clinical and Movement Neurosciences, Queen Square Institute of Neurology, University College London, London, UK.
  • Saito Y; Queen Square Brain Bank for Neurological Disorders, Institute of Neurology, University College London, London, UK.
  • Foroud T; Department of Neuropathology, Metropolitan Institute of Gerontology, Tokyo, Japan.
  • Warner TT; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Hasegawa K; Department of Clinical and Movement Neurosciences, Queen Square Institute of Neurology, University College London, London, UK.
  • Vidal R; Queen Square Brain Bank for Neurological Disorders, Institute of Neurology, University College London, London, UK.
  • Murayama S; Division of Neurology, Sagamihara National Hospital, Sagamihara, Japan.
  • Revesz T; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Ghetti B; Molecular Research Centre for Children's Mental Development, United School of Child Development, University of Osaka, Osaka, Japan.
  • Hasegawa M; Queen Square Brain Bank for Neurological Disorders, Institute of Neurology, University College London, London, UK.
  • Lashley T; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London, UK.
  • Scheres SHW; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Goedert M; Department of Brain and Neurosciences, Metropolitan Institute of Medical Science, Tokyo, Japan.
Nature ; 610(7933): 791-795, 2022 10.
Article em En | MEDLINE | ID: mdl-36108674

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Química Encefálica / Microscopia Crioeletrônica / Doença por Corpos de Lewy / Alfa-Sinucleína Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Química Encefálica / Microscopia Crioeletrônica / Doença por Corpos de Lewy / Alfa-Sinucleína Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido