Higher-order epistasis and phenotypic prediction.

Zhou, Juannan; Wong, Mandy S; Chen, Wei-Chia; Krainer, Adrian R; Kinney, Justin B; McCandlish, David M

Zhou, Juannan; Wong, Mandy S; Chen, Wei-Chia; Krainer, Adrian R; Kinney, Justin B; McCandlish, David M.

Afiliação

Zhou J; Department of Biology, University of Florida, Gainesville, FL 32611.
Wong MS; Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.
Chen WC; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.
Krainer AR; Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.
Kinney JB; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.
McCandlish DM; Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.

Proc Natl Acad Sci U S A ; 119(39): e2204233119, 2022 09 27.

Article em En | MEDLINE | ID: mdl-36129941

Assuntos

Epistasia Genética; Precursores de RNA; Teorema de Bayes; Mapeamento Cromossômico; Biologia Computacional; Genótipo; Humanos; Modelos Genéticos; Mutação; Fenótipo; Splicing de RNA

Palavras-chave

Gaussian processes; genetic interaction; genotypephenotype map; protein G; splicing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Precursores de RNA / Epistasia Genética Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article

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