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Lack of EGFR catalytic activity in hepatocytes improves liver regeneration following DDC-induced cholestatic injury by promoting a pro-restorative inflammatory response.
Lazcanoiturburu, Nerea; García-Sáez, Juan; González-Corralejo, Carlos; Roncero, Cesáreo; Sanz, Julián; Martín-Rodríguez, Carlos; Valdecantos, M Pilar; Martínez-Palacián, Adoración; Almalé, Laura; Bragado, Paloma; Calero-Pérez, Silvia; Fernández, Almudena; García-Bravo, María; Guerra, Carmen; Montoliu, Lluis; Segovia, José Carlos; Valverde, Ángela M; Fabregat, Isabel; Herrera, Blanca; Sánchez, Aránzazu.
Afiliação
  • Lazcanoiturburu N; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid (UCM), Health Research Institute of the 'Hospital Clínico San Carlos' (IdISSC), Madrid, Spain.
  • García-Sáez J; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid (UCM), Health Research Institute of the 'Hospital Clínico San Carlos' (IdISSC), Madrid, Spain.
  • González-Corralejo C; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid (UCM), Health Research Institute of the 'Hospital Clínico San Carlos' (IdISSC), Madrid, Spain.
  • Roncero C; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid (UCM), Health Research Institute of the 'Hospital Clínico San Carlos' (IdISSC), Madrid, Spain.
  • Sanz J; Anatomical Pathology Service of the 'Clínica Universidad de Navarra', Madrid, Spain.
  • Martín-Rodríguez C; Department of Psychiatry, Legal Medicine and Anatomical Pathology, Faculty of Medicine, UCM, Madrid, Spain.
  • Valdecantos MP; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid (UCM), Health Research Institute of the 'Hospital Clínico San Carlos' (IdISSC), Madrid, Spain.
  • Martínez-Palacián A; 'Alberto Sols' Biomedical Research Institute, Spanish National Research Council and Autonomous University of Madrid (IIBM, CSIC-UAM), Madrid, Spain.
  • Almalé L; Biomedical Research Networking Center in Diabetes and Associated Metabolic Disorders of the Carlos III Health Institute (CIBERDEM-ISCIII), Madrid, Spain.
  • Bragado P; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid (UCM), Health Research Institute of the 'Hospital Clínico San Carlos' (IdISSC), Madrid, Spain.
  • Calero-Pérez S; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid (UCM), Health Research Institute of the 'Hospital Clínico San Carlos' (IdISSC), Madrid, Spain.
  • Fernández A; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid (UCM), Health Research Institute of the 'Hospital Clínico San Carlos' (IdISSC), Madrid, Spain.
  • García-Bravo M; 'Alberto Sols' Biomedical Research Institute, Spanish National Research Council and Autonomous University of Madrid (IIBM, CSIC-UAM), Madrid, Spain.
  • Guerra C; Biomedical Research Networking Center in Diabetes and Associated Metabolic Disorders of the Carlos III Health Institute (CIBERDEM-ISCIII), Madrid, Spain.
  • Montoliu L; National Center for Biotechnology (CNB-CSIC), Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain.
  • Segovia JC; Cell Technology Division, Research Center for Energy, Environment and Technology (CIEMAT), Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain.
  • Valverde ÁM; Advanced Therapies Mixed Unit, 'Fundación Jiménez Díaz' University Hospital Health Research Institute (CIEMAT/IIS-FJD), Madrid, Spain.
  • Fabregat I; Molecular Oncology Programme, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
  • Herrera B; National Center for Biotechnology (CNB-CSIC), Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain.
  • Sánchez A; Cell Technology Division, Research Center for Energy, Environment and Technology (CIEMAT), Biomedical Research Networking Center on Rare Diseases (CIBERER-ISCIII), Madrid, Spain.
J Pathol ; 258(3): 312-324, 2022 11.
Article em En | MEDLINE | ID: mdl-36148647

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatopatias / Regeneração Hepática Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Pathol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Espanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatopatias / Regeneração Hepática Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Pathol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Espanha