Curculigoside Represses the Proliferation and Metastasis of Osteosarcoma via the JAK/STAT and NF-&#954;B Signaling Pathways.

Guo, Huiwen; Zheng, Lixiang; Guo, Yepin; Han, Lu; Yu, Jing; Lai, Fuchong

Curculigoside Represses the Proliferation and Metastasis of Osteosarcoma via the JAK/STAT and NF-κB Signaling Pathways.

Guo, Huiwen; Zheng, Lixiang; Guo, Yepin; Han, Lu; Yu, Jing; Lai, Fuchong.

Afiliação

Guo H; College of Traditional Chinese Medicine, Jiangxi University of Chinese Medicine.
Zheng L; College of Traditional Chinese Medicine, Jiangxi University of Chinese Medicine.
Guo Y; College of Humanities, Jiangxi University of Chinese Medicine.
Han L; College of Humanities, Jiangxi University of Chinese Medicine.
Yu J; College of Humanities, Jiangxi University of Chinese Medicine.
Lai F; Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province.

Biol Pharm Bull ; 45(10): 1466-1475, 2022.

Article em En | MEDLINE | ID: mdl-36184504

Assuntos

Neoplasias Ósseas; Osteossarcoma; Animais; Apoptose; Benzoatos; Neoplasias Ósseas/tratamento farmacológico; Caderinas; Caspase 3/metabolismo; Linhagem Celular Tumoral; Proliferação de Células; Glucosídeos; Humanos; Janus Quinases/metabolismo; Janus Quinases/farmacologia; Janus Quinases/uso terapêutico; Camundongos; Camundongos Nus; NF-kappa B/metabolismo; Osteossarcoma/tratamento farmacológico; Transdução de Sinais; Proteína X Associada a bcl-2

Palavras-chave

Janus kinase 2 (JAK2); curculigoside; nuclear factor-κB (NF-κB); osteosarcoma; signal transducer and activator of transcription 3 (STAT3)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Osteossarcoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Biol Pharm Bull Assunto da revista: BIOQUIMICA / FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article

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