Revisiting scrub typhus: A neglected tropical disease.
Comp Immunol Microbiol Infect Dis
; 90-91: 101888, 2022.
Article
em En
| MEDLINE
| ID: mdl-36252451
ABSTRACT
Scrub typhus is an under diagnosed re-emerging vector borne disease caused by an intracellular gram negative bacteria, Orientia. The disease is commonly prevalent in rural and hilly areas of Tsutsugumashi triangle. The diagnosis of the disease is very challenging due to similarity of its early symptoms with other febrile illnesses, like dengue and COVID 19, as well as non-availability of rapid, reliable and cost-effective methods. Moreover, the diverse clinical presentation in severe cases make it significant health problem. The occupational and behavioral risks responsible for the transmission lead to urgent need of vaccine development against the disease. The complete knowledge about its pathogenesis and the interaction with host's immune cells may help the scientists in developing the appropriate diagnostic methods as well as the vaccines.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Orientia tsutsugamushi
/
Tifo por Ácaros
/
Vacinas
/
Doenças Negligenciadas
/
COVID-19
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
Comp Immunol Microbiol Infect Dis
Ano de publicação:
2022
Tipo de documento:
Article