Flexible acoustic lens-based surface acoustic wave device for manipulation and directional transport of micro-particles.

ABSTRACT

Microfluidics is an emerging technology that is playing increasingly important roles in biomedical and pharmaceutical research and development. Surface acoustic waves (SAWs) have been combined with microfluidics technology to establish a SAW-based microfluidics technology that uses the unique interaction between the two techniques to manipulate substances effectively in fluids on the surface of a substrate. This paper reports a method to generate SAWs using conventional planar ultrasonic transducers and acoustic lenses. Additionally, this method is introduced to manipulate particles effectively on a substrate surface. It is demonstrated that the particle positions can be manipulated precisely in any direction on the substrate surface, thus enabling high-precision particle manipulation. We also proposed the generation of nonplanar SAWs via appropriate design of the acoustic lens and realized directional particle transport. In addition, structures to enhance forward-propagating acoustic beams are proposed. The proposed method has potential for use in microfluidics and biomedical applications, allowing tasks such as flexible cell manipulation on a chip to be performed without complex design or micromachining.