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Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome.
Vernia, Santiago; Lee, Alexandra; Kennedy, Norman J; Han, Myoung Sook; Isasa, Marta; Cavanagh-Kyros, Julie; Roy, Armanda; Syed, Aafreen; Chaudhry, Shanzah; Edwards, Yvonne J K; Gygi, Steven P; Gao, Guangping; Davis, Roger J.
Afiliação
  • Vernia S; Medical Research Council, London Institute of Medical Sciences, Du Cane Road, London W12 0NN, United Kingdom.
  • Lee A; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.
  • Kennedy NJ; Program in Molecular Medicine, Chan Medical School, University of Massachusetts, Worcester, MA 01605.
  • Han MS; Program in Molecular Medicine, Chan Medical School, University of Massachusetts, Worcester, MA 01605.
  • Isasa M; Program in Molecular Medicine, Chan Medical School, University of Massachusetts, Worcester, MA 01605.
  • Cavanagh-Kyros J; Department of Cell Biology, Harvard Medical School, Harvard University, Boston, MA 01451.
  • Roy A; Program in Molecular Medicine, Chan Medical School, University of Massachusetts, Worcester, MA 01605.
  • Syed A; Program in Molecular Medicine, Chan Medical School, University of Massachusetts, Worcester, MA 01605.
  • Chaudhry S; Program in Molecular Medicine, Chan Medical School, University of Massachusetts, Worcester, MA 01605.
  • Edwards YJK; Program in Molecular Medicine, Chan Medical School, University of Massachusetts, Worcester, MA 01605.
  • Gygi SP; Program in Molecular Medicine, Chan Medical School, University of Massachusetts, Worcester, MA 01605.
  • Gao G; Department of Cell Biology, Harvard Medical School, Harvard University, Boston, MA 01451.
  • Davis RJ; Horae Gene Therapy Center, Chan Medical School, University of Massachusetts, Worcester, MA 01605.
Proc Natl Acad Sci U S A ; 119(44): e2210434119, 2022 11.
Article em En | MEDLINE | ID: mdl-36282921
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome Metabólica / PPAR alfa Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome Metabólica / PPAR alfa Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido