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Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug.
Lee, BoRa; Kim, Dae Gyu; Lee, Aram; Kim, Young Mi; Cui, Lianji; Kim, Sunghoon; Choi, Inhee.
Afiliação
  • Lee B; Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, Korea.
  • Kim DG; Medicinal Bioconvergence Research Center, Institute for Artificial Intelligence and Biomedical Research, College of Pharmacy and College of Medicine, Interdisciplinary Biomedical Center, Gangnam Severance Hospital, Yonsei University, Seoul, Korea.
  • Lee A; Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, Korea.
  • Kim YM; Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, Korea.
  • Cui L; Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, Korea.
  • Kim S; Medicinal Bioconvergence Research Center, Institute for Artificial Intelligence and Biomedical Research, College of Pharmacy and College of Medicine, Interdisciplinary Biomedical Center, Gangnam Severance Hospital, Yonsei University, Seoul, Korea.
  • Choi I; Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, Korea.
J Enzyme Inhib Med Chem ; 38(1): 51-66, 2023 Dec.
Article em En | MEDLINE | ID: mdl-36305287
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pulmonares / Antineoplásicos Limite: Humans Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pulmonares / Antineoplásicos Limite: Humans Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article