[OPTIC NEURITIS - CLASSIFICATION, MANAGEMENT AND TREATMENT].
Harefuah
; 161(10): 645-651, 2022 Oct.
Article
em He
| MEDLINE
| ID: mdl-36315205
ABSTRACT
INTRODUCTION:
Optic neuritis is an inflammatory condition of the optic nerve, frequently the first manifestation of a central nervous system disease. While typical optic neuritis is strongly associated with multiple sclerosis, the etiology of atypical optic neuritis varies. The visual and the systemic prognosis, as well as the management depend on the suspected etiology. The understanding and the classification of atypical optic neuritis evolved significantly since the discovery of the anti-aquaporin4 (AQP4) and the anti-myelin oligodendrocyte glycoprotein (MOG) antibodies as biomarkers and pathologic causes of neuromyelitis optica spectrum disorder (NMOSD) and MOG-associated disorder (MOGAD) respectively. Additional causes of optic neuritis include multiple autoimmune and infectious diseases. About one third of optic neuritis cases are idiopathic. Correct and timely diagnosis of the optic neuritis etiology is crucial for proper treatment initiation and for reducing long term visual and systemic disability.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neurite Óptica
/
Neuromielite Óptica
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
He
Revista:
Harefuah
Ano de publicação:
2022
Tipo de documento:
Article