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Pathway-based integration of multi-omics data reveals lipidomics alterations validated in an Alzheimer's disease mouse model and risk loci carriers.
Garcia-Segura, Monica Emili; Durainayagam, Brenan R; Liggi, Sonia; Graça, Gonçalo; Jimenez, Beatriz; Dehghan, Abbas; Tzoulaki, Ioanna; Karaman, Ibrahim; Elliott, Paul; Griffin, Julian L.
Afiliação
  • Garcia-Segura ME; Department of Brain Sciences, Imperial College London, London, UK.
  • Durainayagam BR; Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Liggi S; Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Graça G; UK-Dementia Research Institute (UK-DRI) at Imperial College London, London, UK.
  • Jimenez B; Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Dehghan A; Section of Bioinformatics, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Tzoulaki I; Section of Bioanalytical Chemistry and the National Phenome Centre, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Karaman I; UK-Dementia Research Institute (UK-DRI) at Imperial College London, London, UK.
  • Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
  • Griffin JL; MRC Centre for Environment and Health, Imperial College London, London, UK.
J Neurochem ; 164(1): 57-76, 2023 01.
Article em En | MEDLINE | ID: mdl-36326588

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Neurochem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Neurochem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido