Condensin DC loads and spreads from recruitment sites to create loop-anchored TADs in <i>C. elegans</i>.

Kim, Jun; Jimenez, David S; Ragipani, Bhavana; Zhang, Bo; Street, Lena A; Kramer, Maxwell; Albritton, Sarah E; Winterkorn, Lara H; Morao, Ana K; Ercan, Sevinc

Condensin DC loads and spreads from recruitment sites to create loop-anchored TADs in C. elegans.

Kim, Jun; Jimenez, David S; Ragipani, Bhavana; Zhang, Bo; Street, Lena A; Kramer, Maxwell; Albritton, Sarah E; Winterkorn, Lara H; Morao, Ana K; Ercan, Sevinc.

Afiliação

Kim J; Department of Biology and Center for Genomics and Systems Biology, New York University, New York, United States.
Jimenez DS; Department of Biology and Center for Genomics and Systems Biology, New York University, New York, United States.
Ragipani B; Department of Biology and Center for Genomics and Systems Biology, New York University, New York, United States.
Zhang B; UCSF HSW, San Francisco, United States.
Street LA; Department of Biology and Center for Genomics and Systems Biology, New York University, New York, United States.
Kramer M; Department of Biology and Center for Genomics and Systems Biology, New York University, New York, United States.
Albritton SE; Department of Biology and Center for Genomics and Systems Biology, New York University, New York, United States.
Winterkorn LH; Department of Biology and Center for Genomics and Systems Biology, New York University, New York, United States.
Morao AK; Department of Biology and Center for Genomics and Systems Biology, New York University, New York, United States.
Ercan S; Department of Biology and Center for Genomics and Systems Biology, New York University, New York, United States.

Elife ; 112022 Nov 04.

Article em En | MEDLINE | ID: mdl-36331876

Assuntos

Caenorhabditis elegans; Regulação da Expressão Gênica; Animais; Caenorhabditis elegans/genética; Mecanismo Genético de Compensação de Dose; Cromossomo X/genética

Palavras-chave

3D genome organization; C. elegans; Hi-C; TADs; X-chromosome; chromosomes; condensin; gene expression; genetics; genomics; loop extrusion

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Caenorhabditis elegans Limite: Animals Idioma: En Revista: Elife Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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