Anti-inflammatory effects of PRIMA-1<sup>MET</sup> (mutant p53 reactivator) induced by inhibition of nuclear factor-&#954;B on rheumatoid arthritis fibroblast-like synoviocytes.

Adib, Mehrnoosh; Taghadosi, Mahdi; Tahmasebi, Mohammad Naghi; Sharafat Vaziri, Arash; Jamshidi, Ahmadreza; Mahmoudi, Mahdi; Farhadi, Elham

Anti-inflammatory effects of PRIMA-1^MET (mutant p53 reactivator) induced by inhibition of nuclear factor-κB on rheumatoid arthritis fibroblast-like synoviocytes.

Adib, Mehrnoosh; Taghadosi, Mahdi; Tahmasebi, Mohammad Naghi; Sharafat Vaziri, Arash; Jamshidi, Ahmadreza; Mahmoudi, Mahdi; Farhadi, Elham.

Afiliação

Adib M; Immunology Department, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Taghadosi M; Immunology Department, Kermanshah University of Medical Sciences, Kermanshah, Iran. mtaghad@gmail.com.
Tahmasebi MN; Center of Orthopedic Trans-Disciplinary Applied Research, Tehran University of Medical Sciences, Tehran, Iran.
Sharafat Vaziri A; Center of Orthopedic Trans-Disciplinary Applied Research, Tehran University of Medical Sciences, Tehran, Iran.
Jamshidi A; Rheumatology Research Center, Tehran University of Medical Sciences, Shariati Hospital, Kargar Ave, PO-BOX: 1411713137, Tehran, Iran.
Mahmoudi M; Rheumatology Research Center, Tehran University of Medical Sciences, Shariati Hospital, Kargar Ave, PO-BOX: 1411713137, Tehran, Iran.
Farhadi E; Inflammation Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Inflammopharmacology ; 31(1): 385-394, 2023 Feb.

Article em En | MEDLINE | ID: mdl-36350424

Assuntos

Artrite Reumatoide; Sinoviócitos; Humanos; NF-kappa B/metabolismo; Inibidor de NF-kappaB alfa/metabolismo; Inibidor de NF-kappaB alfa/farmacologia; Proteína Supressora de Tumor p53/metabolismo; Interleucina-6/metabolismo; Artrite Reumatoide/metabolismo; Fibroblastos; Anti-Inflamatórios/farmacologia; Células Cultivadas; Proliferação de Células

Palavras-chave

Fibroblast-like synoviocytes; NF-κB; Noxa; P53; PRIMA-1MET; Rheumatoid arthritis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Sinoviócitos Limite: Humans Idioma: En Revista: Inflammopharmacology Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Irã

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