PR-DUB preserves Polycomb repression by preventing excessive accumulation of H2Aub1, an antagonist of chromatin compaction.

Bonnet, Jacques; Boichenko, Iulia; Kalb, Reinhard; Le Jeune, Mathilde; Maltseva, Svetlana; Pieropan, Mattia; Finkl, Katja; Fierz, Beat; Müller, Jürg

Bonnet, Jacques; Boichenko, Iulia; Kalb, Reinhard; Le Jeune, Mathilde; Maltseva, Svetlana; Pieropan, Mattia; Finkl, Katja; Fierz, Beat; Müller, Jürg.

Afiliação

Bonnet J; Laboratory of Chromatin Biology, Max-Planck Institute of Biochemistry, 82152 Martinsried, Germany.
Boichenko I; Laboratory of Biophysical Chemistry of Macromolecules, Institute of Chemical Sciences and Engineering (ISIC), Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Kalb R; Laboratory of Chromatin Biology, Max-Planck Institute of Biochemistry, 82152 Martinsried, Germany.
Le Jeune M; Laboratory of Biophysical Chemistry of Macromolecules, Institute of Chemical Sciences and Engineering (ISIC), Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Maltseva S; Laboratory of Chromatin Biology, Max-Planck Institute of Biochemistry, 82152 Martinsried, Germany.
Pieropan M; Laboratory of Chromatin Biology, Max-Planck Institute of Biochemistry, 82152 Martinsried, Germany.
Finkl K; Laboratory of Chromatin Biology, Max-Planck Institute of Biochemistry, 82152 Martinsried, Germany.
Fierz B; Laboratory of Biophysical Chemistry of Macromolecules, Institute of Chemical Sciences and Engineering (ISIC), Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Müller J; Laboratory of Chromatin Biology, Max-Planck Institute of Biochemistry, 82152 Martinsried, Germany.

Genes Dev ; 36(19-20): 1046-1061, 2022 10 01.

Article em En | MEDLINE | ID: mdl-36357125

Assuntos

Cromatina; Proteínas de Drosophila; Animais; Proteínas do Grupo Polycomb/genética; Proteínas do Grupo Polycomb/metabolismo; Histonas/metabolismo; Proteínas de Drosophila/genética; Proteínas de Drosophila/metabolismo; Nucleossomos; Drosophila/genética; Complexo Repressor Polycomb 1/genética; Complexo Repressor Polycomb 1/metabolismo

Palavras-chave

Asx; Bap1; Drosophila; H2AK119 monoubiquitination; PR-DUB; PRC1; Polycomb

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Proteínas de Drosophila Limite: Animals Idioma: En Revista: Genes Dev Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha

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