Prenatal inflammation shapes microglial immune response into adulthood.
Trends Immunol
; 43(12): 953-955, 2022 12.
Article
em En
| MEDLINE
| ID: mdl-36357264
ABSTRACT
Hayes and collaborators recently unraveled that maternal immune activation in mice led to a long-lasting decrease in microglial immune reactivity. Thus, microglia exhibited a reduced immune response to a second proinflammatory stressor in adulthood. This altered microglial response impacted both astrocytic reactivity and neuronal circuitry.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Microglia
/
Inflamação
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Trends Immunol
Assunto da revista:
ALERGIA E IMUNOLOGIA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Argentina