Age-related decrease in appetitive associative memory in fruit flies.
J Exp Biol
; 225(21)2022 11 01.
Article
em En
| MEDLINE
| ID: mdl-36373856
ABSTRACT
Memory scores are dynamic across developmental stages. In particular, memory scores typically decrease from late adolescence into old age, reflecting complex changes in mnemonic and sensory-motor faculties, metabolic and motivational changes, and changes in cognitive strategy as well. In Drosophila melanogaster, such age-related decreases in memory scores have been studied intensely for the association of odours with electric shock punishment. We report that odour-sucrose reward memory scores likewise decrease as the flies age. This was observed after one-trial and after two-trial conditioning, and for both immediate testing and recall tests 1 day later. This decrease was particularly pronounced in relatively young animals, in the first 2-3â
weeks after adult hatching, and was more pronounced in female than in male flies.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Drosophila melanogaster
/
Memória
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
Idioma:
En
Revista:
J Exp Biol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Alemanha