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Myeloid-derived itaconate suppresses cytotoxic CD8+ T cells and promotes tumour growth.
Zhao, Hongyun; Teng, Da; Yang, Lifeng; Xu, Xincheng; Chen, Jiajia; Jiang, Tengjia; Feng, Austin Y; Zhang, Yaqing; Frederick, Dennie T; Gu, Lei; Cai, Li; Asara, John M; Pasca di Magliano, Marina; Boland, Genevieve M; Flaherty, Keith T; Swanson, Kenneth D; Liu, David; Rabinowitz, Joshua D; Zheng, Bin.
Afiliação
  • Zhao H; Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
  • Teng D; Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
  • Yang L; Department of Chemistry, Princeton University, Princeton, NJ, USA.
  • Xu X; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
  • Chen J; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Jiang T; Department of Chemistry, Princeton University, Princeton, NJ, USA.
  • Feng AY; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
  • Zhang Y; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Frederick DT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Gu L; Epigenetics Laboratory, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
  • Cai L; Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
  • Asara JM; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
  • Pasca di Magliano M; Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA, USA.
  • Boland GM; Epigenetics Laboratory, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
  • Flaherty KT; Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Swanson KD; Division of Signal Transduction, Beth Israel Deaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Liu D; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
  • Rabinowitz JD; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
  • Zheng B; Cancer Biology Program, University of Michigan, Ann Arbor, MI, USA.
Nat Metab ; 4(12): 1660-1673, 2022 12.
Article em En | MEDLINE | ID: mdl-36376563
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Supressoras Mieloides / Neoplasias Limite: Animals Idioma: En Revista: Nat Metab Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Supressoras Mieloides / Neoplasias Limite: Animals Idioma: En Revista: Nat Metab Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos