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Generation and multiomic profiling of a TP53/CDKN2A double-knockout gastroesophageal junction organoid model.
Zhao, Hua; Cheng, Yulan; Kalra, Andrew; Ma, Ke; Zheng, Yueyuan; Ziman, Benjamin; Tressler, Caitlin; Glunde, Kristine; Shin, Eun Ji; Ngamruengphong, Saowanee; Khashab, Mouen; Singh, Vikesh; Anders, Robert A; Jit, Simran; Wyhs, Nicolas; Chen, Wei; Li, Xu; Lin, De-Chen; Meltzer, Stephen J.
Afiliação
  • Zhao H; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.
  • Cheng Y; Division of Gastroenterology and Hepatology, Department of Medicine and Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Kalra A; Clinical Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 Yanta West Road, Xi'an 710061, Shaanxi, China.
  • Ma K; Division of Gastroenterology and Hepatology, Department of Medicine and Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Zheng Y; Division of Gastroenterology and Hepatology, Department of Medicine and Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Ziman B; Division of Gastroenterology and Hepatology, Department of Medicine and Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Tressler C; Einstein Healthcare Network, Philadelphia, PA 19136, USA.
  • Glunde K; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
  • Shin EJ; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.
  • Ngamruengphong S; Russell H. Morgan Department of Radiology and Radiological Science, Division of Cancer Imaging Research, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Khashab M; Russell H. Morgan Department of Radiology and Radiological Science, Division of Cancer Imaging Research, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Singh V; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Anders RA; Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Jit S; Division of Gastroenterology and Hepatology, Department of Medicine and Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Wyhs N; Division of Gastroenterology and Hepatology, Department of Medicine and Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Chen W; Division of Gastroenterology and Hepatology, Department of Medicine and Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Li X; Division of Gastroenterology and Hepatology, Department of Medicine and Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Lin DC; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Meltzer SJ; Division of Gastroenterology and Hepatology, Department of Medicine and Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Sci Transl Med ; 14(673): eabq6146, 2022 11 30.
Article em En | MEDLINE | ID: mdl-36449602
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Organoides / Proteína Supressora de Tumor p53 Tipo de estudo: Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Organoides / Proteína Supressora de Tumor p53 Tipo de estudo: Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos