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Targeting integrated stress response with ISRIB combined with imatinib treatment attenuates RAS/RAF/MAPK and STAT5 signaling and eradicates chronic myeloid leukemia cells.
Dudka, Wioleta; Hoser, Grazyna; Mondal, Shamba S; Turos-Korgul, Laura; Swatler, Julian; Kusio-Kobialka, Monika; Wolczyk, Magdalena; Klejman, Agata; Brewinska-Olchowik, Marta; Kominek, Agata; Wiech, Milena; Machnicki, Marcin M; Seferynska, Ilona; Stoklosa, Tomasz; Piwocka, Katarzyna.
Afiliação
  • Dudka W; Laboratory of Cytometry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093, Warsaw, Poland.
  • Hoser G; Center of Postgraduate Medical Education, Laboratory of Flow Cytometry, Warsaw, Poland.
  • Mondal SS; Laboratory of Bioinformatics, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland.
  • Turos-Korgul L; Laboratory of Cytometry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093, Warsaw, Poland.
  • Swatler J; Laboratory of Cytometry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093, Warsaw, Poland.
  • Kusio-Kobialka M; Laboratory of Cytometry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093, Warsaw, Poland.
  • Wolczyk M; Laboratory of Cytometry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093, Warsaw, Poland.
  • Klejman A; Laboratory of Animal Models, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland.
  • Brewinska-Olchowik M; Laboratory of Cytometry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093, Warsaw, Poland.
  • Kominek A; Laboratory of Cytometry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093, Warsaw, Poland.
  • Wiech M; Laboratory of Cytometry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093, Warsaw, Poland.
  • Machnicki MM; Department of Tumor Biology and Genetics, Medical University of Warsaw, Warsaw, Poland.
  • Seferynska I; Department of Hematology, Institute of Hematology and Blood Transfusion, Warsaw, Poland.
  • Stoklosa T; Department of Tumor Biology and Genetics, Medical University of Warsaw, Warsaw, Poland.
  • Piwocka K; Laboratory of Cytometry, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093, Warsaw, Poland. k.piwocka@nencki.edu.pl.
BMC Cancer ; 22(1): 1254, 2022 Dec 02.
Article em En | MEDLINE | ID: mdl-36460969
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Leucemia Mieloide Limite: Animals / Humans Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Polônia
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Leucemia Mieloide Limite: Animals / Humans Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Polônia