[Sarcopenia in patients with pancreatic cancer, an independant prognostic factor]. / Sarkopenie als unabhängiger Prognosefaktor bei Pankreaskarzinom.
Z Gastroenterol
; 61(10): 1365-1370, 2023 Oct.
Article
em De
| MEDLINE
| ID: mdl-36482058
ABSTRACT
BACKGROUND:
Pancreatic cancer is despite modern diagnostic tools and treatment regimen associated with poor outcome. Many patients show cachexia and sarcopenia.METHODS:
In a retrospective analysis the SMI (cm²/m²) was measured by determining the skelettal muscle area in a computed tomography image at lumbar vertebrae 3. Further clinical parameters were measured to determine the outcome.RESULTS:
The mean survival after diagnosis in the population with sarcopenia was significantly lower (14,4 vs 17,7 months, p=0,046). Significantly shorter survival was also seen for higher age (p=0,006), no tumor resection (p=0,004), metastases (p=0,002) and high CA19-9 level (p=0,002)CONCLUSION:
Sarcopenia is an indipendant prognostic factor in patients with pancreatic cancer. SMI should be measured clinical practice and further studies are necessary to asses a potential therapeutic strategy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Pancreáticas
/
Músculo Esquelético
/
Sarcopenia
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
De
Revista:
Z Gastroenterol
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Alemanha