Exosomal miR-125a-5p regulates T lymphocyte subsets to promote silica-induced pulmonary fibrosis by targeting TRAF6.

Ding, Mingcui; Pei, Yangqing; Zhang, Chengpeng; Qi, Yuanmeng; Xia, Jiarui; Hao, Changfu; Yao, Wu

Ding, Mingcui; Pei, Yangqing; Zhang, Chengpeng; Qi, Yuanmeng; Xia, Jiarui; Hao, Changfu; Yao, Wu.

Afiliação

Ding M; Department of Occupational Health and Occupational Disease, School of Public Health, Zhengzhou University, Zhengzhou 450001, Henan, China.
Pei Y; Department of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450001, Henan, China.
Zhang C; Department of Occupational Health and Occupational Disease, School of Public Health, Zhengzhou University, Zhengzhou 450001, Henan, China.
Qi Y; Department of Occupational Health and Occupational Disease, School of Public Health, Zhengzhou University, Zhengzhou 450001, Henan, China.
Xia J; Department of Occupational Health and Occupational Disease, School of Public Health, Zhengzhou University, Zhengzhou 450001, Henan, China.
Hao C; Department of child and Adolecence health, School of public health, Zhengzhou University, Zhengzhou 450001, Henan, China. Electronic address: haochangfu@126.com.
Yao W; Department of Occupational Health and Occupational Disease, School of Public Health, Zhengzhou University, Zhengzhou 450001, Henan, China. Electronic address: yaowu@zzu.edu.cn.

Ecotoxicol Environ Saf ; 249: 114401, 2023 Jan 01.

Article em En | MEDLINE | ID: mdl-36508789

Assuntos

Exossomos; MicroRNAs; Fibrose Pulmonar; Dióxido de Silício; Silicose; Animais; Camundongos; Proliferação de Células; MicroRNAs/genética; MicroRNAs/metabolismo; Fibrose Pulmonar/induzido quimicamente; Fibrose Pulmonar/genética; Fibrose Pulmonar/patologia; Dióxido de Silício/toxicidade; Silicose/genética; Silicose/patologia; Subpopulações de Linfócitos T/metabolismo; Subpopulações de Linfócitos T/patologia; Fator 6 Associado a Receptor de TNF/genética; Fator 6 Associado a Receptor de TNF/metabolismo; Exossomos/genética; Exossomos/metabolismo

Palavras-chave

Exosomes; MiR-125a-5p; Pulmonary fibrosis; T lymphocyte; TRAF6

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Silicose / Dióxido de Silício / MicroRNAs / Exossomos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Ecotoxicol Environ Saf Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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