Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny-part III: how is substance-mediated thyroid hormone imbalance in pregnant/lactating rats or their progeny related to neurodevelopmental effects?
Crit Rev Toxicol
; 52(7): 546-617, 2022 08.
Article
em En
| MEDLINE
| ID: mdl-36519295
Palavras-chave
OECD TG 443); Thyroxine (T4); acoustic startle response; adverse outcome pathway (AOP); cognitive function (learning and memory); deiodinase (DIO); developmental neurotoxicity (DNT) study (OECD TG 426); extended one generation reproductive toxicity study (EOGRTS; mode-of-action (MoA); motor activity; sodium-iodide symporter (NIS); thyroid hormone clearance; thyroid peroxidase (TPO); triiodothyronine (T3); uridine diphosphate glucuronyltransferase (UGT)
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Glândula Tireoide
/
Doenças do Sistema Endócrino
Tipo de estudo:
Prognostic_studies
/
Qualitative_research
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Crit Rev Toxicol
Assunto da revista:
TOXICOLOGIA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos