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Activation of cDCs and iNKT cells contributes to triptolide-induced hepatotoxicity via STING signaling pathway and endoplasmic reticulum stress.
Chen, Xin; Yu, Zixun; Nong, Cheng; Xue, Rufeng; Zhang, Mingxuan; Zhang, Yiying; Sun, Lixin; Zhang, Luyong; Wang, Xinzhi.
Afiliação
  • Chen X; New Drug Screening Center, Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, Nanjing, 210009, China.
  • Yu Z; New Drug Screening Center, Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, Nanjing, 210009, China.
  • Nong C; New Drug Screening Center, Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, Nanjing, 210009, China.
  • Xue R; Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.
  • Zhang M; New Drug Screening Center, Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, Nanjing, 210009, China.
  • Zhang Y; Division of Biosciences, University College London, London, WC1E 6BT, UK.
  • Sun L; New Drug Screening Center, Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, Nanjing, 210009, China.
  • Zhang L; New Drug Screening Center, Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, Nanjing, 210009, China. lyzhang@cpu.edu.cn.
  • Wang X; Center for Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, 510006, China. lyzhang@cpu.edu.cn.
Cell Biol Toxicol ; 39(4): 1753-1772, 2023 08.
Article em En | MEDLINE | ID: mdl-36520315
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células T Matadoras Naturais / Doença Hepática Induzida por Substâncias e Drogas Limite: Humans Idioma: En Revista: Cell Biol Toxicol Assunto da revista: TOXICOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células T Matadoras Naturais / Doença Hepática Induzida por Substâncias e Drogas Limite: Humans Idioma: En Revista: Cell Biol Toxicol Assunto da revista: TOXICOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China