Representation matters: a call for inclusivity and equity in heart failure clinical trials.
Eur Heart J Suppl
; 24(Suppl L): L45-L48, 2022 Dec.
Article
em En
| MEDLINE
| ID: mdl-36545232
ABSTRACT
The burden of heart failure remains substantial worldwide, and heart failure with reduced ejection fraction (HFrEF) affects approximately half of this population. Despite this global prevalence of HFrEF, the majority of contemporary clinical trials in HFrEF have underenrolled individuals from minoritized sex, gender, race, ethnicity, and socioeconomic groups. Moreover, significant disparities in access to HFrEF treatment and outcomes exist across these same strata. We provide a call to action for the inclusion of diverse populations in HFrEF clinical trials; catalogue several barriers to adequate representation in HFrEF clinical trials; and propose strategies to broaden inclusivity in future HFrEF trials.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Revista:
Eur Heart J Suppl
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos