Protective Effects of <i>Atractylodis lancea</i> Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-&#954;B and Keap1/Nrf2 Signaling Pathways In Vitro and In Vivo.

Shi, Kun; Xiao, Yangxin; Dong, Yan; Wang, Dongpeng; Xie, Ying; Tu, Jiyuan; Xu, Kang; Zhou, Zhongshi; Cao, Guosheng; Liu, Yanju

Protective Effects of Atractylodis lancea Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-κB and Keap1/Nrf2 Signaling Pathways In Vitro and In Vivo.

Shi, Kun; Xiao, Yangxin; Dong, Yan; Wang, Dongpeng; Xie, Ying; Tu, Jiyuan; Xu, Kang; Zhou, Zhongshi; Cao, Guosheng; Liu, Yanju.

Afiliação

Shi K; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Xiao Y; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Dong Y; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Wang D; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Xie Y; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Tu J; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Xu K; Center for Hubei TCM Processing Technology Engineering, Wuhan 430065, China.
Zhou Z; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Cao G; Center for Hubei TCM Processing Technology Engineering, Wuhan 430065, China.
Liu Y; College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.

Int J Mol Sci ; 23(24)2022 Dec 17.

Article em En | MEDLINE | ID: mdl-36555773

Assuntos

Lesão Pulmonar Aguda; NF-kappa B; Receptor 4 Toll-Like; Animais; Ratos; Lesão Pulmonar Aguda/induzido quimicamente; Lesão Pulmonar Aguda/tratamento farmacológico; Lesão Pulmonar Aguda/metabolismo; Glutationa/metabolismo; Proteína 1 Associada a ECH Semelhante a Kelch/metabolismo; Lipopolissacarídeos/toxicidade; Pulmão/patologia; Fator 2 Relacionado a NF-E2/metabolismo; NF-kappa B/metabolismo; Transdução de Sinais; Receptor 4 Toll-Like/metabolismo; Extratos Vegetais/farmacologia; Atractylodes/química

Palavras-chave

acute lung injury; ethanolic extract of Atractylodis rhizoma; inflammatory response; oxidative stress

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NF-kappa B / Receptor 4 Toll-Like / Lesão Pulmonar Aguda Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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